From Marc Ladanyi and colleagues at Memorial Sloan-Kettering: EGFR-TK resistance in lung cancer

http://www.ncbi.nlm.nih.gov/pubmed/21135146

Clin Cancer Res. 2010 Dec 6. [Epub ahead of print]
Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR mutant lung cancer: Distinct natural history of patients with tumors harboring the T790M mutation.
Oxnard GR, Arcila ME, Sima C, Riely GJ, Chmielecki J, Kris MG, Pao W, Ladanyi M, Miller VA.