Thursday, July 14, 2011

From MD Anderson: Disparities in symptom burden in lung cancer patients

http://www.ncbi.nlm.nih.gov/pubmed/21751190

Cancer. 2011 Jul 12. doi: 10.1002/cncr.26312. [Epub ahead of print]
Early referral to supportive care specialists for symptom burden in lung cancer patients: A Comparison of Non-Hispanic Whites, Hispanics, and Non-Hispanic Blacks.
Reyes-Gibby CC, Anderson KO, Shete S, Bruera E, Yennurajalingam S.
Source
Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas. creyes@mdanderson.org.
Abstract
BACKGROUND:
Effective management of symptoms in cancer patients requires early intervention. This study assessed whether the timing of referral to the Supportive Care Center (SCC) and symptom burden outcome varied by race or ethnicity in lung cancer patients who had been seen at a tertiary cancer center.

METHODS:
Non-Hispanic white (n = 752), Hispanic (n = 111), and non-Hispanic black (n = 117) patients with nonsmall cell lung cancer comprised this sample. Data on sociodemographic factors, stage of disease, comorbid conditions, and symptom severity (pain, depressed mood, fatigue) served as potential predictor variables.

RESULTS:
Whereas the mean time (15 months; median = 7 months) from initial presentation at the cancer center to referral to the SCC did not vary by race or ethnicity, we found that Hispanics and non-Hispanic blacks had higher symptom burden when they first presented at the cancer center than non-Hispanic whites. Severe pain, depressed mood, and fatigue were significant predictors for early referral (<7 months) of non-Hispanic whites, but only severe fatigue (P <.05) was predictive of early referral for Hispanics and non-Hispanic blacks. Furthermore, while the proportion of non-Hispanic white patients reporting severe pain, depressed mood, and fatigue significantly decreased (P <.001) at first follow-up visit after referral to the SCC; among Hispanics, improvement was only observed for depressed mood. No improvement in any of these symptoms was observed for non-Hispanic blacks.

CONCLUSIONS:
Whereas the timing of referral to supportive services did not vary by race, disparities in symptom burden outcomes persisted. Additional studies are needed to validate our findings. Cancer 2011;. © 2011 American Cancer Society.

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