Thursday, October 20, 2011

From Wash U: Depression after a heart attack

http://www.ncbi.nlm.nih.gov/pubmed/22010201

Circ Cardiovasc Qual Outcomes. 2011 Oct 18. [Epub ahead of print]
Depression and Rehospitalization Following Acute Myocardial Infarction.
Reese RL, Freedland KE, Steinmeyer BC, Rich MW, Rackley JW, Carney RM.
Source
Department of Psychology, Department of Psychiatry, and Department of Medicine, Washington University School of Medicine, St Louis, MO.

Abstract
BACKGROUND: Whether depressive disorders predict rehospitalization after AMI is unknown. METHODS AND RESULTS: <0.001; major depression adjusted hazard ratio, 2.54; 95% CI, 1.84-3.53; P<0.001), had more hospitalizations (minor, P<0.001; major, P<0.001) and emergency department visits (minor, P=0.003; major, P<0.001), and spent more days in the hospital (minor, P<0.001; major, P<0.001). The interview and questionnaire methods of assessing depression did not significantly differ in their overall accuracy of predicting rehospitalization.ConclusionsDepressive disorders increase the risk of rehospitalization after AMI. Future work should focus on developing multivariable models to predict risk of rehospitalization after AMI, and depression should be included in these.

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