From UChicagoNews: New technique reveals unseen information in DNA code

http://news.uchicago.edu/article/2012/05/17/new-technique-reveals-unseen-information-dna-code

New technique reveals unseen information in DNA code

By Quinn Eastman, Rachel Steinhardt, Steve Koppes

MAY 17, 2012

“This is a major breakthrough in that TAB-Seq allows precise mapping of all 5-hydroxymethylcytosine sites in a mammalian genome using well-established, next-generation DNA sequencing methods,” said Joseph Ecker, a professor at the Salk Institute for Biological Studies, who was not involved in theCell study. “The study showed very clearly that deriving useful knowledge about this poorly understood epigenetic regulator requires determination of the exact locations of 5hmC with base-level accuracy. I expect that their new method will immediately become widely adopted.”