Saturday, July 28, 2012

Declines in Prostate Cancer Incidence After Changes in Screening Recommendations

http://www.ncbi.nlm.nih.gov/pubmed/22826149


 2012 Jul 23:1-2. doi: 10.1001/archinternmed.2012.2768. [Epub ahead of print]

Declines in Prostate Cancer Incidence After Changes in Screening Recommendations.



"On August 5, 2008, the US Preventive Services Task Force (USPSTF) recommended against screening men 75 years or older for prostate cancer.For men younger than 75 years, the USPSTF maintained its previous recommendation: “ . . . the evidence is insufficient to recommend for or against routine screening for prostate cancer. . . ”(p915) (although this recommendation was changed to “do not screen” younger men in the 2011 guidelines). This study evaluates trends in prostate cancer incidence following the release of the 2008 USPSTF recommendation. If the revised recommendation led to a decline in prostate cancer screening rates, there should be a corresponding decline in the incidence of early-stage tumors among men 75 and older relative to trends in the incidence of late-stage tumors and early-stage tumors in younger men.
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There was an immediate decline in the incidence of early-stage prostate cancer tumors among men 75 years and older after the USPSTF recommended against screening this group. The magnitude of the decline was larger than the secular decline in the incidence rate for other stage and age groups. The results are consistent with the hypothesis that the revision of the USPSTF recommendations led to a small to moderate decline in prostate cancer screening rates. Many men 75 years and older may continue to receive screening tests. Some of the decline in the incidence of late-stage tumors may be attributable to decreases in screening via digital rectal examinations."



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