Glaxo Stops MAGE-A3 Lung Cancer Study

by Zacks Equity Research   Published on April 03, 2014

The randomized, blinded, placebo-controlled study evaluated the efficacy and safety of the MAGE-A3 cancer immunotherapeutic in patients suffering from stage IB, II and IIIA completely resected non-small cell lung cancer (NSCLC), whose tumors expressed the MAGE-A3 gene. Glaxo decided to stop the study after it was found impossible to identify a sub-population of gene-signature positive NSCLC patients that may benefit from the MAGE-A3 cancer immunotherapeutic