Tuesday, April 12, 2016

Gastroesophageal Reflux Affects Sleep Quality in Snoring Obese Children

 2016 Mar;19(1):12-19. Epub 2016 Mar 22.

Gastroesophageal Reflux Affects Sleep Quality in Snoring Obese Children.

Author information

  • 1Department of Pediatrics, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.
  • 2Division of Pediatric Gastroenterology, Ohio State University, Columbus, OH, USA.
  • 3Department of Pediatrics,Nationwide Children's Hospital, Columbus, OH, USA.
  • 4Department of Pediatrics, Ohio State University, Columbus, OH, USA.



This study was performed to evaluate the quality of sleep in snoring obese children without obstructive sleep apnea (OSA); and to study the possible relationship between sleep interruption and gastroesophageal reflux (GER) in snoring obese children.


Study subjects included 13 snoring obese children who were referred to our sleep lab for possible sleep-disordered breathing. Patients underwent multichannel intraluminal impedance and esophageal pH monitoring with simultaneous polysomnography. Exclusion criteria included history of fundoplication, cystic fibrosis, and infants under the age of 2 years. Significant association between arousals and awakenings with previous reflux were defined by symptom-association probability using 2-minute intervals.


Sleep efficiency ranged from 67-97% (median 81%). A total of 111 reflux episodes (90% acidic) were detected during sleep, but there were more episodes per hour during awake periods after sleep onset than during sleep (median 2.3 vs. 0.6, p=0.04). There were 279 total awakenings during the sleep study; 56 (20.1%) of them in 9 patients (69.2%) were preceded by reflux episodes (55 acid, 1 non-acid). In 5 patients (38.5%), awakenings were significantly associated with reflux.


The data suggest that acid GER causes sleep interruptions in obese children who have symptoms of snoring or restless sleep and without evidence of OSA.

1 comment:

  1. who is snoring, you will become frustrated, and above all, your holistic health and well- being will be seriously damagedzquiet