Tuesday, April 12, 2016

Gastroesophageal Reflux Affects Sleep Quality in Snoring Obese Children

 2016 Mar;19(1):12-19. Epub 2016 Mar 22.

Gastroesophageal Reflux Affects Sleep Quality in Snoring Obese Children.

Author information

  • 1Department of Pediatrics, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.
  • 2Division of Pediatric Gastroenterology, Ohio State University, Columbus, OH, USA.
  • 3Department of Pediatrics,Nationwide Children's Hospital, Columbus, OH, USA.
  • 4Department of Pediatrics, Ohio State University, Columbus, OH, USA.

Abstract

PURPOSE:

This study was performed to evaluate the quality of sleep in snoring obese children without obstructive sleep apnea (OSA); and to study the possible relationship between sleep interruption and gastroesophageal reflux (GER) in snoring obese children.

METHODS:

Study subjects included 13 snoring obese children who were referred to our sleep lab for possible sleep-disordered breathing. Patients underwent multichannel intraluminal impedance and esophageal pH monitoring with simultaneous polysomnography. Exclusion criteria included history of fundoplication, cystic fibrosis, and infants under the age of 2 years. Significant association between arousals and awakenings with previous reflux were defined by symptom-association probability using 2-minute intervals.

RESULTS:

Sleep efficiency ranged from 67-97% (median 81%). A total of 111 reflux episodes (90% acidic) were detected during sleep, but there were more episodes per hour during awake periods after sleep onset than during sleep (median 2.3 vs. 0.6, p=0.04). There were 279 total awakenings during the sleep study; 56 (20.1%) of them in 9 patients (69.2%) were preceded by reflux episodes (55 acid, 1 non-acid). In 5 patients (38.5%), awakenings were significantly associated with reflux.

CONCLUSION:

The data suggest that acid GER causes sleep interruptions in obese children who have symptoms of snoring or restless sleep and without evidence of OSA.

1 comment:

  1. who is snoring, you will become frustrated, and above all, your holistic health and well- being will be seriously damagedzquiet

    ReplyDelete