Tuesday, November 28, 2017

PTPR-γ

Liver Link between Obesity and Diabetes Highlights New Therapeutic Target


"In summary, our results indicate that the increased hepatic PTPR-γ level observed in obesity is sufficient to cause insulin resistance and hence unveil PTPR-γ as a new target for anti-T2DM therapy,” the authors continue. “Our data suggest that means aimed at decreasing hepatic PTPR-γ expression/activity should improve T2DM. This goal could be achieved by development of specific PTPR-γ inhibitors."

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