Wednesday, November 28, 2012

The impact of corruption on multidrug-resistant tuberculosis

http://www.ncbi.nlm.nih.gov/pubmed/22941550


 2012 Sep;40(3):792-3. doi: 10.1183/09031936.00180911.

The impact of corruption on multidrug-resistant tuberculosis: a quantitative assessment.



The emergence of antimicrobial resistance is a complex problem driven by numerous interconnected factors, many of which are linked to the use of antimicrobials [2]. According to CAMINERO [3], at a community level four main groups of potential factors associated with the selection of resistance and the generation of MDR-TB under epidemic conditions exist: 1) non-implementation of DOTS (Directly Observed Treatment Short course) and DOTS expansion strategies; 2) inadequate supply or poor quality of drugs; 3) patients’ inadequate drug intake; and 4) other factors such as the magnitude of HIV infection.
Corruption is a complex problem which threatens the impact of public investments, healthcare access and services, equity and outcomes [4]. There is mounting evidence on the negative effects of corruption on the health and welfare of citizens and on the consequences of corruption in multiple health areas or processes, especially in the regulation of product quality and the distribution and use of drugs. More globally, corruption was shown to affect all domains of life from education to economic performance [5] and it could also impact on health outcomes.

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