Lida P. Hariri, Mari Mino-Kenudson, Eugene J. Mark, and Melissa J. Suter (2012) In Vivo Optical Coherence Tomography: The Role of the Pathologist. Archives of Pathology & Laboratory Medicine: December 2012, Vol. 136, No. 12, pp. 1492-1501.
SPECIAL SECTION—HOUSTON LUNG SYMPOSIUM, PART II
In Vivo Optical Coherence Tomography: The Role of the Pathologist
Lida P. Hariri , MD, PhD; Mari Mino-Kenudson , MD; Eugene J. Mark , MD; Melissa J. Suter , PhD
From the Departments of Pathology (Drs Hariri, Mino-Kenudson, and Mark), the Pulmonary and Critical Care Unit (Dr Suter), and the Wellman Center for Photomedicine, Massachusetts General Hospital, Boston (Drs Hariri and Suter); and the Harvard Medical School, Cambridge, Massachusetts (Drs Hariri, Mino-Kenudson, Mark, and Suter).
Optical coherence tomography (OCT) is a nondestructive, high-resolution imaging modality, providing cross-sectional, architectural images at near histologic resolutions, with penetration depths up to a few millimeters. Optical frequency domain imaging is a second-generation OCT technology that has equally high resolution with significantly increased image acquisition speeds and allows for large area, high-resolution tissue assessments. These features make OCT and optical frequency domain imaging ideal imaging techniques for surface and endoscopic imaging, specifically when tissue is unsafe to obtain and/or suffers from biopsy sampling error. This review focuses on the clinical impact of OCT in coronary, esophageal, and pulmonary imaging and the role of the pathologist in interpreting high-resolution OCT images as a complement to standard tissue pathology.
No comments:
Post a Comment