http://www.ncbi.nlm.nih.gov/pubmed/21730004
Ther Adv Respir Dis. 2011 Jul 5. [Epub ahead of print]
Targeted therapy of non-small-cell lung carcinoma.
Tiwari D, Brodie SA, Brandes JC.
Source
Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Abstract
The rapid expansion of novel technologies in cancer research over the past several years has led to a dramatically improved understanding of the molecular biology of lung cancer. As a consequence, novel targeted therapies are rapidly being developed. In this review, we summarize the most important molecular pathways in lung cancer and describe the clinical evidence for the development of therapies against these targets.
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