From the Mayo Clinic: Appropriateness of the treatment of fatigued patients with stage IV cancer

http://www.ncbi.nlm.nih.gov/pubmed/22915355

Support Care Cancer. 2012 Aug 23. [Epub ahead of print]

Appropriateness of the treatment of fatigued patients with stage IV cancer.

Cheville AL, Shen T, Chang M, Basford JR.

Source

Department of Physical Medicine and Rehabilitation, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA, cheville.andrea@mayo.edu.

Abstract

BACKGROUND:

Fatigue among patients with cancer is prevalent, disabling, and treatable. While fatigue management guidelines have been in place for a decade, their use remains unclear.

METHODS:

We surveyed 160 patients with stage IV lung (40), breast (40), colon (40), and prostate (40) cancer who reported moderate to severe fatigue (i.e., >5 of 10 on an 11-point numerical rating scale). Participants were queried about receipt of treatments in fatigue management domains emphasized in the National Comprehensive Cancer Network guidelines: general management strategies, activity enhancement, psychosocial strategies, and pharmaceuticals.

RESULTS:

The cohort was half male, had a mean age of 67, and reported an average fatigue rating of 6.4. Participants reported treatment or receipt of specific guidance in the fatigue management domains as follows: general management strategies 16.8 %, activity enhancement 11.9 %, psychosocial strategies 9.9 %, and pharmaceuticals 37.3 %. Fatigue >7 of 10 increased the likelihood of instruction in activity enhancement but no other domain.

CONCLUSION:

The low rates of guideline-congruent treatment reported here are concerning, particularly as better validated behavioral treatments were the least prescribed.