Feast Or Famine: The Switch That Helps Your Liver Adapt
"These results suggest that inhibiting SETDB2 could lessen certain metabolic side effects such as weight gain and insulin resistance in patients taking steroids for inflammatory disease," Osborne added. "Since SETDB2 only affects a subset of steroid hormone-regulated genes related to metabolism, we think this strategy would not interfere with steroids' anti-inflammatory effects.
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