Ann Surg Oncol. 2011 Aug 6. [Epub ahead of print]
Molecular Predictors of Prognosis in Lung Cancer.
Lin J, Beer DG.
Section of Thoracic Surgery, University of Michigan, Ann Arbor, MI, USA.
Lung carcinoma is the leading cause of cancer mortality worldwide. Currently, cancer staging and prognosis are determined using histopathology and clinical factors such as lymph node status. However, even the earliest stage of non-small cell lung carcinoma has a widely varying prognosis. In this review, the evolution and refinement of molecular predictors of prognosis in lung carcinoma are described.