From Helsinki U: Fallopian tube carcinoma-an occupational disease?

http://www.ncbi.nlm.nih.gov/pubmed/21805475

Int J Cancer. 2011 Jul 29. doi: 10.1002/ijc.26337. [Epub ahead of print]
Occupation and risk of primary fallopian tube carcinoma in nordic countries.
Riska A, Martinsen J, Kjaerheim K, Lynge E, Sparen P, Tryggvadottir L, Weiderpass E, Pukkala E.
Source
Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Helsinki, Finland. annika.riska@pp.inet.fi.

Abstract
The aetiology of primary Fallopian tube carcinoma (PFTC) is poorly understood. Occupational exposures may contribute to PFTC risk. We studied incidence of PFTC in occupational categories in the Nordic female population aged 30-64 years during the 1960, 1970, 1980/1981 and/or 1990 censuses in Denmark, Finland, Iceland, Norway and Sweden. Standardized incidence ratios (SIRs) for the years following inclusion in the study up to 2005 were calculated for 53 occupations; the expected numbers of cases were based on PFTC incidence in the national populations. Altogether 2206 PFTC cases were detected during follow up via data linkages with the Nordic cancer registries. Significantly increased risks of PFTC were observed for smelting workers (SIR 3.99, 95% confidence interval 1.46-8.68,Obs=6), artistic workers (2.64, 1.44-4.43,Obs=14), hairdressers (2.18, 1.41-3.22,Obs=25), packers (1.62, 1.11-2.29,Obs=32), nurses (1.49, 1.14- 1.92,Obs=60), shop workers (1.25, 1.07-1.46,Obs=159) and clerical workers (1.20, 1.07-1.35,Obs=271) and these sustained over times and different Nordic countries. There was a non-significant increased risk for PFTC among welders, printers, painters and chemical process workers. The risk was significantly and consistently low for women working in farming (0.68, 0.47-0.95,Obs=34) and among economically inactive women (0.88, 0.82-0.94,Obs=833). The possible role of occupational exposures to the PFTC risks found in this study must be further evaluated in studies with a possibility to adjust for possible confounding factors, such as reproductive and life-style factors, which was not possible in our study.