Obesity Promotes Cancer Growth
Monday, October 15, 2012 12:05 PM
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"Previous research has clearly established a link between obesity and cancer risk and shown that obesity is associated with a poorer prognosis, according to Mikhail Kolonin, an associate professor at the Institute of Molecular Medicine at the University of Texas Health Science Center at Houston.
He and his colleagues examined how obesity might promote cancer progression. Their findings were published in the Oct. 15 issue of the journal Cancer Research.
"Our earlier studies led us to hypothesize that fat tissue called white adipose tissue, which is the fat tissue that expands in individuals who are obese, is itself directly involved and that it is not just diet and lifestyle that are important," Kolonin explained in a journal news release.
Their initial results confirmed this theory. They found that tumors grew much faster in obese mice than in lean mice that ate the same diet. The researchers also found that obese mice had far more white adipose tissue cells (adipose stromal cells) than lean mice, which led them to focus on these cells."
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