J Gerontol A Biol Sci Med Sci. 2013 Nov 27. [Epub ahead of print]
Obesity in the Sarcopenia Era.
Source
Sticht Center on Aging, Medical Center Boulevard, Winston-Salem, NC 27157. skritche@wakehealth.edu.
"In community-dwelling older adults, the linkage between lean mass and strength is not especially strong, and some interventions that are effective in increasing lean mass do not appear to affect strength (2,3). Furthermore, intentional weight loss in obese older adults does not necessarily reduce muscle strength, despite significant reductions in muscle mass (4). In contrast to what might be predicted by the sarcopenia hypothesis, there have been five moderate to large clinical trials showing that weight loss improves physical performance and that this effect is additive to the benefits of exercise (5–9). Furthermore, the degree of functional improvement is correlated with the extent of adipose tissue loss (10). The benefits of physical activity seem to be blunted in obese older adults (11), and high levels of adiposity accelerate aging-related loss of lean mass (12). Concerns that intentional weight loss might predispose overweight or obese older persons to a higher mortality risk appear unwarranted (13)."
No comments:
Post a Comment