Nat Rev Clin Oncol. 2011 Sep 6. doi: 10.1038/nrclinonc.2011.137. [Epub ahead of print]
Chemotherapy: Advanced Hodgkin lymphoma-balancing toxicity and cure.
Lim SH, Johnson PW.
Source
Cancer Research UK Centre, Faculty of Medicine, University of Southampton, Tremona Road, Southampton SO16 6YD, UK.
PMID: 21894205 [PubMed - as supplied by publisher]
The combination of doxorubicin, bleomycin, vincristine and dacarbazine (ABVD) has emerged as a standard of care in advanced-stage Hodgkin lymphoma over the past four decades. Clinicians treating patients with cancer frequently walk a tightrope where the requirements of efficacy have to be balanced against the morbidity caused by the treatment.
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