Need another reason to work out? Walking, running, glucagon-like peptide-1, and appetite in women

http://www.ncbi.nlm.nih.gov/pubmed/22619704

J Obes. 2012;2012:730409. Epub 2012 Apr 29.

Influence of running and walking on hormonal regulators of appetite in women.

Larson-Meyer DE, Palm S, Bansal A, Austin KJ, Hart AM, Alexander BM.

Source

Department of Family and Consumer Sciences, University of Wyoming, Laramie, WY 82071, USA.

Abstract

Nine female runners and ten walkers completed a 60 min moderate-intensity (70% VO(2)max) run or walk, or 60 min rest in counterbalanced order. Plasma concentrations of the orexogenic peptide ghrelin, anorexogenic peptides peptide YY (PYY), glucagon-like peptide-1 (GLP-1), and appetite ratings were measured at 30 min interval for 120 min, followed by a free-choice meal. Both orexogenic and anorexogenic peptides were elevated after running, but no changes were observed after walking. Relative energy intake (adjusted for cost of exercise/rest) was negative in the meal following running (-194 ± 206 kcal) versus walking (41 ± 196 kcal) (P = 0.015), although both were suppressed (P < 0.05) compared to rest (299 ± 308 and 284 ± 121 kcal, resp.). The average rate of change in PYY and GLP-1 over time predicted appetite in runners, but only the change in GLP-1 predicted hunger (P = 0.05) in walkers. Results provide evidence that exercise-induced alterations in appetite are likely driven by complex changes in appetite-regulating hormones rather than change in a single gut peptide.