"The ultimate goal is to preferentially detect consequential cancer while avoiding detection of inconsequential disease." (Problematic;currently difficult/impossible to differentiate)

http://www.ncbi.nlm.nih.gov/pubmed/23896967

JAMA. 2013 Jul 29. doi: 10.1001/jama.2013.108415. [Epub ahead of print]

Overdiagnosis and Overtreatment in Cancer: An Opportunity for Improvement.

Esserman LJ, Thompson IM, Reid B.

Source

University of California, San Francisco

"The ultimate goal is to preferentially detect consequential cancer while avoiding detection of inconsequential disease."